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An 11 kg Malignant Fibrous Histiocytoma in a 54-Year-Old Patient: A Case Report

Author(s): Ghadir M.R | Sarkeshikian S | Amjadi M.R | Ghanooni A.H | Khan Ahmadi N

Journal: Qom University of Medical Sciences Journal
ISSN 1735-7799

Volume: 5;
Issue: 3;
Start page: 97;
Date: 2011;
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Keywords: Histiocytoma | Malignant Fibrous | Sarcoma | Retroperitoneal Neoplasms

Background and Objectives: Malignant fibrous histiocytoma (MFH) is a soft tissue sarcoma of undifferentiated mesenchymal cell origin which is considered the most common soft tissue sarcoma in adults. It commonly occurs in the 5th and 6th decades with a 2-to-1 male to female ratio. It most frequently occurs in the extremities and retroperitoneum. Most of it is derived from soft tissues and some of it from bone tissue. In this study, we introduce a patient who had MFH in retroperitoneal area and at the time of diagnosis the tumor size and weight had reached a significant level.Case Report: The patient is a 54-year-old male that referred to the hospital with complaints of pain and fullness in the abdomen. His pain had started from two years ago and had been accompanied with early satiation, bloating, weight gain and hypertension. On physical examination, asymmetric enhancement was visible. After diagnosis of mass and investigation of its development in abdomen and pelvic with CTscan, the patient was underwent operation and a mass with about 11kg of weigh was resected. During pathologic investigation, high grade spindle cell sarcoma and malignant fibrous histiocytoma were reported. After resection of tumor, the abdominal pain of patient disappeared and additionally his blood pressure came back to normal levels.
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