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1,3-Dipolar cycloaddition of azomethine ylide from Phtaloylimidophenylalanyl-2-hydroxymethylaziridine1,3-Dipolar cycloaddition of azomethine ylide from Phtaloylimidophenylalanyl-2-hydroxymethylaziridine

Author(s): Assia Keniche | Wassila Drici | Mohamed Zakaria Slimani | Abdelmoumen Mezrai | Joseph Kajima Mulengi

Journal: Mediterranean Journal of Chemistry
ISSN 2028-3997

Volume: 2;
Issue: 4;
Start page: 583;
Date: 2013;
Original page

Phtaloylimidophenylalanyl-2-hydroxymethylaziridine has been used as a starting material to yield azomethine ylide through thermal opening and was then involved into 1,3-dipolar cycloaddition reactions. Different five-membered adducts were obtained and were fully identified. The latter might be considered useful starting materials for further functionalization to provide novel compounds of biological interest.
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