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2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine

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Author(s): Balapragalathan Thappali Jothikrishnan | Sriram Narasimhan | Suban Syed Shafi

Journal: Molbank
ISSN 1422-8599

Volume: 2010;
Issue: 1;
Start page: M668;
Date: 2010;
Original page

Keywords: 5-(1 | 3-benzodioxol-5-yl)-3-(pyrazin-2-yl)-4 | 5-dihydro-1H-pyrazole-1-carbo-thioamide | 4-chlorophenacyl bromide | microwave

ABSTRACT
A simple method for the synthesis of a pyrazolyl thiazole derivative containing a piperonal moiety was developed. Thus, 2-{5-(1,3-benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine was synthesized using microwave irradiation and characterized by NMR, IR and LCMS data.
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