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2. Isolation, characterisation and formulation properties of a new plant gum obtained from mangifera indica

Author(s): Anoop Kumar Singh | R. Panner Selvam | T. Sivakumar

Journal: International Journal of Pharmaceutical and Biomedical Research (IJPBR)
ISSN 0976-0350

Volume: 01;
Issue: 02;
Start page: 35;
Date: 2010;
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Keywords: Mangifera indica | mango gum | tablet binder | excipients

This study elucidated the physical, thermal, sorption and functional properties of a gum obtained from the stem of mangifera indica were characterized viz. elemental analysis, Fourier transmittance infra red, particle size analysis, thermo gravimetric analysis, differential scanning colorimetry, scanning electron microscopy and X-ray powder diffraction. Mangifera indica gum had a glass transition temperature (Tg) and melting peak of 90 and 318.795°C, respectively. This material showed a 14.59 % loss in weight at 200oC. The sample had peaks at approximately 21o, 29o, and 39o 2θ degrees of 2-theta (θ) in the X-ray powder diffraction pattern. Elemental analysis showed that gum of mangifera indica contains 35.62, 6.12, 56.57 and 1.67% of carbon, hydrogen, oxygen and nitrogen, respectively. The results obtained in this study establish the fundamental characteristics of mangifera indica gum. The in vitro drug release was more than 90 % at 30 min. Tablets with 5% w/w binder concentration showed optimum results than standard binder, thus conclusion was drawn that mango gum was found to be useful for the preparation of uncoated tablet dosage form.
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