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An 8-year evaluation of nasal and paranasal sinuses malignant neoplasms in Tehran University of Medical Sciences hospitals

Author(s): Mohsen Naraghi | Ebrahim Karimi | OmbolBanin Motamed | Mona Heidarali

Journal: Iranian Journal of Otorhinolaryngology
ISSN 2251-7251

Volume: 21;
Issue: 56;
Start page: 67;
Date: 2009;
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Keywords: Chemotherapy | Conventional resection | Endoscopic surgery | Malignant neoplasm | Paranasal sinuses | Radiotherapy

Introduction: Nasal and paranasal sinuses malignant neoplasms are usually diagnosed in advanced stages because of non-specific and benign symptoms. In this study we evaluated the symptoms, pathology and treatment of paranasal sinuses malignancies in patients admitted to Tehran University of Medical Sciences affiliated hospitals. Material and Methods: In this descriptive study, medical files of patients diagnosed with paranasal sinus malignancies and admitted to Imam Khomeini and Amir Aalam hospitals between 2000-2007 were evaluated. Results: Of 75 patients, 47 were male and 28 were female. The mean age was 55±14.1 years. The most common sinus involvement was seen in Maxillary sinuses (86.7%) and 18 patients had concurrent involvement of other sinuses. The most common pathology was squamous cell carcinoma (40%) and the most common clinical symptom was nasal obstruction (%28). Distant metastasis was found in 46 patients and 42 patients presented with eye involvement Eleven patients underwent endoscopic resection. Conclusion: The presence of eye involvement and distant metastasis in a large number of the patients showed that diagnosis of paranasal cancers is delayed because of their nonspecific symptoms. Therefore further education of clinical manifestations of paranasal sinus cancers is emphasized. 
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