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Abdominal obesity, metabolic syndrome in type 1 diabetic children and adolescents

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Author(s): Agnieszka Szadkowska | Iwona Pietrzak | Joanna Szlawska | Anna Kozera | Anna Gadzicka | Wojciech Młynarski

Journal: Pediatric Endocrinology, Diabetes and Metabolism
ISSN 2081-237X

Volume: 15;
Issue: 4;
Start page: 233;
Date: 2009;
Original page

Keywords: abdominal obesity | metabolic syndrome | children and adolescents | type 1 diabetes mellitus

ABSTRACT
Introduction: The rapid rising prevalence of childhood obesity is related to the increased risk of cardiovascular morbidities. The type 1 diabetic patients are the group at special risk of macroangiopathy. The aim of the study was to estimate the prevalence of abdominal obesity in type 1 diabetic children compared to the general population, and to estimate the prevalence of metabolic syndrome diagnosed according to IDF criteria in type 1 diabetic children and adolescents. Material and methods: 163 patients with type 1 diabetes mellitus (91 male) aged from 10 to 18 years were included into the study. The diabetes duration ranged from 0.5 to 15.2 years. The height, weight, waist circumference, body fat and blood pressure were measured. HbA1c and plasma lipids concentrations were examined. Body mass index, waist/height ratio (WHtR) and daily dose of insulin were calculated. Estimated glucose disposal rate (eGDR) as indicator of insulin resistance was calculated according to own formula. Results: Abdominal obesity diagnosed as WHtR >0.5 was found in 19 patients (11.7%, CI95% 6.7-16.6). Associations between WHtR and HbA1c (r=0.18; p=0.027), cholesterol-HDL (r=-0.22; p=0.004), systolic (β=0.37; p

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