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Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review

Author(s): Masoodi, Ibrahim | Farooq, Omar | Ahmad, Iqbal | Bhat, Mohammad Yaseen | Ahmad, Nazir | Wani, Hamid-ullah | Dar, Javeed Ahmad

Journal: GMS German Medical Science
ISSN 1612-3174

Volume: 8;
Start page: Doc32;
Date: 2010;
Original page

Keywords: acute disseminated encephalomyelitis | tuberculosis

Acute disseminated encephalomyelitis (ADEM) also known as post infectious encephalomyelitis is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurological symptoms and disability. It may follow vaccination in children or infection. Viral infection like measles, rubella, influenza, Epstein bar, HIV, herpes, cytomegalusvirus (CMV) and West Nile virus have been implicated in the causation. Among bacteria, group A hemolytic streptococcus, mycoplasma pneumonia, Chlamydia, Rickettesia and leptospira have been shown to cause ADEM. There are few reports of ADEM due to tuberculosis (TB). We describe acute disseminated encephalomyelitis due to tuberculosis in a 35 year old female who initially started with neuropsychiatric manifestations and later developed florid neurological deficit and classical magnetic resonance imaging (MRI) lesions suggestive of the disease. The patient recovered completely after antitubercular therapy and is following our clinic for the last 12 months now.

Tango Jona
Tangokurs Rapperswil-Jona

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