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Agenesis of the corpus callosum and septum pellucidum together with a multiple layered duramater

Author(s): Sargon MF | Brohi RA | Ozeksi P | Tonak AK | Cumhur M

Journal: Neuroanatomy
ISSN 1303-1783

Volume: 1;
Issue: 1;
Start page: 2;
Date: 2002;
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Keywords: Neuroanatomy | Anatomy | Duramater | Brain

During the removal of the brain in a 55-year-old male cadaver, a multiple layered duramater which was covering the left cerebral hemisphere was observed. In this cadaver, the endosteal layer of duramater was formed from 5 layers and there was a normal meningeal layer over the left cerebral hemisphere. Tissue specimens were taken for light microscopy from each of the endosteal layers and all of these 5 layers were found to be the endosteal layer of duramater. Following the mid-sagittal section of the brain, agenesis of the corpus callosum and septum pellucidum were also observed in this cadaver. In addition to all these findings, the gross anatomic appearance of the telencephalon was very abnormal, when compared with the normal brains. Agenesis of the corpus callosum and septum pellucidum are very rare abnormalities and they are usually associated with neurological disorders. However, a multiple layered duramater has not been reported previously. In conclusion, we believe that the combination of these three abnormalities is a unique entity and they might have been formed depending upon early embryological developmental abnormalities.
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