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Aloe Vera High Molecular Weight Fractions as Carbohydratebased Immune Adjuvants

Author(s): Akira Yagi

Journal: Journal of Gastroenterology and Hepatology Research
ISSN 2224-3992

Volume: 2;
Issue: 5;
Start page: 568;
Date: 2013;
Original page

Keywords: Aloe vera high molecular weight fractions | Therapeutic efficacy | Hepatic periportal fibrosis | Type 2 diabetes | Bedsores

By using the patented hyper-dry system after washing out colouredmaterials with running water, aloe high molecular fractions (AHM)were obtained in original and natural form containing less than 10ppm of barbaloin. AHM mainly contained high molecular fractions,such as polysaccharide (acemannan) and glycoprotein (verectin)showing immunomodulatory and anti-inflammatory activities. On thebasis of chemical and biochemical properties, AHM were examinedfor the therapy designed by the implementation of well-controlledclinical trials, and exhibited the efficacy as immunomodulators forviral infection-induced hepatic periportal fibrosis and type 2 diabeticpatients, and as wound and ulcer-healing ointment to patientssuffering from bedsore. Therefore, AHM were considered to be anovel low-cost and safe drug of natural origin, indicating a possibletherapeutic efficacy in prevention of age-related diseases.
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