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ANALGESIC ACTIVITY OF ROOT EXTRACT OF SOLANUM MELONGENA LINN ROOT

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Author(s): Srivastava Ashish | Sanjay Yadav

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 2;
Issue: 5;
Start page: 1615;
Date: 2011;
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Keywords: Brinjal | Solanum melongena Linn | analgesic activity.

ABSTRACT
The present study was aimed at Pharmacognostic study and biological evaluation of analgesic activity of plants roots. The roots of plants were studies for Pharmacognostic characteristics namely, morphology, microscopy, physicochemical parameters, which can be of utilized in identification/authentication of the plant and/or its roots in crude drug form. The preliminary phytochemical screening of the dry residue was carried out by the chemical test and thin layer chromatographic method. The preliminary phytochemical screening of dry residue showed the presence of Saponins, Alkaloids, Glycoside, and Flavonoids in various extracts. However most of the medicinally potential phytoconstituents were present in methanolic and aqueous extracts. The Hydroalcoholic extract was selected for Biological screening due to high alcoholic-soluble extractive value, high yield of successive alcoholic extract and TLC results. The analgesic screening was done using Hot plate method, Tail immersion methods and acetic acid induced in rats and mice. Hydroalcoholic extract was administered orally at the acute doses of 200mg/kg and 400mg/kg b.w. Several activities on these doses have already been reported. Both the doses showed significant (p
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