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Analgesic activity of various extracts of Punica granatum (Linn) flowers

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Author(s): Chakraborthy Guno

Journal: International Journal of Green Pharmacy
ISSN 0973-8258

Volume: 2;
Issue: 3;
Start page: 145;
Date: 2008;
Original page

Keywords: Analgesic activity | mice | Punica granatum (Linn.)

ABSTRACT
The extracts of flowers of Punica granatum (Linn). (N.O. Family Punicaceae) were investigated for analgesic activity in mice using hot plate method. The flowers of Punica granatum (Linn) were collected from the local market of Mumbai, Maharashtra and were in a dried condition. The dried powdered flowers (500 gm) were extracted in a soxhlet apparatus by using different solvents. Mice weighing 15-25 gm were taken for the experiment. The reaction time of animals in all the groups was noted at 30, 60 and 120 min after drug administration. All data were analyzed with Student-t test. The various extract of the flowers of Punica granatum (Linn) showed significant analgesic activity at a dose of 50 mg/kg body weight. A maximum analgesic activity was found at 60 min, after drug administration, which was equivalent to the standard drug used as morphine sulphate.
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