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Analgesic, CNS Depressant and Anthelmintic Activity of Sarcostemma viminale

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Author(s): Aboli S Girme | Sunil A Nirmal | Rasika D Bhalke | Machindra J Chavan

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 7;
Issue: 2;
Start page: 153;
Date: 2008;
Original page

Keywords: Sarcostemma viminale | Analgesic | CNS depressant | Anthelmintic | Photoactometer | Phere- Tima posthuma

ABSTRACT
Various extracts of Sarcostemma viminale were screened for central analgesic activity by hot plate test, peripheral analgesic activity by acetic acid-induced writhings, CNS depressant activity by pentobarbitone-induced sleep and locomotor activity testing methods and anthelmintic activity on the earthworms Pheretima posthuma. Results showed that petroleum ether and ethyl acetate extracts had good central analgesic activity; ethyl acetate and methanol extracts had good peripheral analgesic activity; chloroform and ethyl acetate extracts had good CNS depressant activity and methanol extract had good anthelmintic activity.

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