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Analysis of Arginine, Glucose, Sucrose, and Polyethylene Glycols using a Wood Charcoal Matrix for MALDI-MS

Author(s): Sunyoung Lee | Jinhee Kim | Hyo-Jik Yang | Seongjae Shin | Jangmi Hong | Jeongkwon Kim

Journal: Mass Spectrometry Letters
ISSN 2233-4203

Volume: 1;
Issue: 1;
Start page: 33;
Date: 2010;

Keywords: Wood charcoal | Polyethylene glycol | Mass spectrometry | MALDI

Wood charcoal was investigated to determine its potential as an alternative matrix for matrix-assisted laser desorption/ionization of various samples. Wood charcoal was an effective matrix for analyzing glucose, sucrose, arginine, and polyethyleneglycols (PEGs), with detection levels of 100 pmol for glucose, 1 nmol for sucrose, 100 pmol for arginine, 100 pmol for PEG 400,1 pmol for PEG 1540, and 10 pmol for PEG 3350. No analyte signal was observed for peptides or proteins.
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