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Anti-Hepatitis B Virus Activity of Flavonoids from Marchantia convoluta

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Author(s): Xiao Jian-bo | Ren Feng-lian | Ming Xu

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 4;
Issue: 2;
Start page: 128;
Date: 2005;
Original page

Keywords: Marchantia convoluta | Flavonoids | Anti-HBV

ABSTRACT
Flavonoids from Marchantia convoluta (MCF) were studied for their ability to inhibit the proliferation of 2.2.15 cells. All concentration of MCF inhibited the secretion of HBsAg and HBeAg in the cultured medium by 2.2.15 cells. Analysis of morphological changes of MCF-treated cells by phase-contrast microscopy revealed a possible mode of action for MCF: inhibition of proliferation of 2.2.15 cells by inducing apoptosis.

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