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Anti-oxidant Activity of 2-hydroxyacetophenone Chalcone

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Author(s): Shaifali Singh

Journal: Journal of Advanced Scientific Research
ISSN 0976-9595

Volume: 2;
Issue: 3;
Start page: 37;
Date: 2011;
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Keywords: Chalcone | 2-hydroxyacetophenone | substituted aldehyde | anti-oxidant activity | 2 | 2-diphenyl-1-picrylhydrazyl.

ABSTRACT
The novel series of chalcone was synthesized by 2-hydroxyacetophenone and substituted aldehyde. The structure of the synthesized compound was elucidated by melting point, retention factor, I.R. spectroscopic technique, 1H NMR and elemental analysis. A series of various substituted chalcone were evaluated for in- vitro anti-oxidant activity by 2, 2-diphenyl-1-picrylhydrazyl method. Among the entire synthesized compound IIf showed the most potent anti-oxidant activity and the other derivatives like IId, IIe, IIg, IIk and IIm was showed mild anti-oxidant activity.
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