Academic Journals Database
Disseminating quality controlled scientific knowledge

Anti-photoaging and Photoprotective Compounds Derived from Marine Organisms

ADD TO MY LIST
 
Author(s): Ramjee Pallela | Yoon Na-Young | Se-Kwon Kim

Journal: Marine Drugs
ISSN 1660-3397

Volume: 8;
Issue: 4;
Start page: 1189;
Date: 2010;
Original page

Keywords: anti-photoaging | photoprotection | UV irradiation | reactive oxygen species (ROS) | matrix metalloproteinases (MMPs)

ABSTRACT
Marine organisms form a prominent component of the oceanic population, which significantly contribute in the production of cosmeceutical and pharmaceutical molecules with biologically efficient moieties. In addition to the molecules of various biological activities like anti-bacterial, anti-cancerous, anti-inflammatory and anti-oxidative etc., these organisms also produce potential photoprotective or anti-photoaging agents, which are attracting present day researchers. Continuous exposure to UV irradiation (both UV-A and UV-B) leads to the skin cancer and other photoaging complications, which are typically mediated by the reactive oxygen species (ROS), generated in the oxidative pathways. Many of the anti-oxidative and anti-photoaging compounds have been identified previously, which work efficiently against photodamage of the skin. Recently, marine originated photoprotective or anti-photoaging behavior was observed in the methanol extracts of Corallina pilulifera (CPM). These extracts were found to exert potent antioxidant activity and protective effect on UV-A-induced oxidative stress in human dermal fibroblast (HDF) cells by protecting DNA and also by inhibiting matrix metalloproteinases (MMPs), a key component in photoaging of the skin due to exposure to UV-A. The present review depicts various other photoprotective compounds from algae and other marine sources for further elaborative research and their probable use in cosmeceutical and pharmaceutical industries.

Tango Jona
Tangokurs Rapperswil-Jona

     Affiliate Program