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Anti Dermatophyte Activities of Eucalyptus camaldulensis in Comparison with Griseofulvin

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Author(s): Mehraban Falahati | Nasim Omidi Tabrizib | Fereshteh Jahaniani

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 4;
Issue: 2;
Start page: 80;
Date: 2005;
Original page

Keywords: Antifungal activities | Eucalyptus camaldulensis | Griseofulvin | Dermatophytes

ABSTRACT
Methanolic leaf extracts of Eucalyptus camaldulensis were investigated for in vitro antifungal activities against Microsporum canis, Microsporum gypseum, Tricophyton rubrum, Tricophyton schoenleinii, Tricophyton mentagrophytes and Epedermophyton floccosum. The studies were carried out using broth dilution method, agar dilution method and inhibitory zone estimation. The effects of the plant extract were compared with those of griseofulvin. Eucalyptus camaldulensis showed antifungal activity against all the dermatophytes tested with MIC values ranging from 0.4 to 1.6 mg/mL using inhibitory zone estimation, 0.4-1.6 mg/mL using agar dilution method and 0.2 to 1.6 mg/mL using broth dilution method. The minimum fungicidal concentration (MFC) of the extracts ranged from 0.8 to 6.4 mg/mL. The results obtained suggest that E. Camaldulensis has anti-dermatophyte activity.

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