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ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACTS OF PLANTS USED IN FOLK MEDICINE

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Author(s): Gupta Raj Narayan | Viswas Kartik | Pathak Manoj | Parihar Surendra Singh | Gupta Alka

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 1;
Issue: 2;
Start page: 529;
Date: 2010;
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Keywords: Achyranthes aspera | Alternanthera pungens | Cynodon dactylon | Lantana camara | Tagetes patula | MIC.

ABSTRACT
The antibacterial activity of the ethanol and aqueous extracts of the leaves of Achyranthes aspera, Alternanthera pungens, Cynodon dactylon, Lantana camara and Tagetes patula was investigated against Bacillus subtilis (MTCC 441) , Staphylococcus aureus (MTCC 3160) and Pseudomonas aeroginosa (MTCC 4673), using agar diffusion technique. Results showed that the only ethanolic extracts of 4 plants species except Alternanthera pungens were effective against all the test microorganisms. The minimum inhibitory concentrations (MIC) of the extracts of ethanol were found to be 25 to 125 mg/ml, while the water based extracts showed no inhibition. The results of the study provide scientific basis for the use of the plant extract in the treatment of wounds and skin diseases. Therefore it is concluded that the active principles possessing antibacterial activity may be extracted from the leaves of Achyranthes aspera, Cynodon dactylon, Lantana camara and Tagetes patula by ethanol.
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