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Antibacterial activity of eight marine microalgae against a few gram negative bacterial pathogens

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Author(s): Krishnika, A*, Bhanupriya, P. B and Beena B. Nair

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 9;
Start page: 3024;
Date: 2011;
Original page

Keywords: Algae | marine microalgae | antibacterial activity

ABSTRACT
In vitro screening of eight marine microalgae Chaetoceros sp., Chlorella sp., Dicrateria sp., Dunaliella sp., Isochrysis sp., Nannochloropsis sp., Synechococcus sp.,and Tetraselmis sp. showed species specific activity in inhibiting the growth of bacteria such as Salmonella paratyphi A, Pseudomonas fluorescens, Shigella boydi,Klebsiella pneumoniae and Escherichia coli. The study reveals that the extracts of Chlorella sp., Nannochloropsis sp., Dunaliella sp., Tetraselmis sp. andIsochrysis sp. have optimal activity against all the pathogenic bacteria studied. Ethanol extracts exhibited best activity against the bacterial pathogens.Tetraselmis sp. showed antibacterial activity against Pseudomonas fluorescens, Klebsiella pneumoniae and Escherichia coli, while Nannochloropsis sp. andDunaliella sp. highly inhibited the growth of Salmonella paratyphi A, Shigella boydi and Pseudomonas fluorescens. The present study confirms the potential useof marine microalgal extract as a source of antibacterial compounds.
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