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ANTIBIOTIC SUSCEPTIBILITY PATTERN OF NOSOCOMIAL ISOLATES OF STAPHYLOCOCCUS HAEMOLYTICUS FROM A TERTIARY CARE HOSPITAL

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Author(s): Vishal Sharma* | Neerja Jindal

Journal: International Journal of Bioassays
ISSN 2278-778X

Volume: 2;
Issue: 3;
Start page: 524;
Date: 2013;
Original page

Keywords: Nosocomial | Methicilllin | Minimum Inhibitory Concentration | Oxacillin | Glycopeptides | Broth Macro Dilution

ABSTRACT
Staphylococcus haemolyticus is a potentially important nosocomial species and is characterized by resistance to multiple antimicrobial agents. This study was undertaken to determine the prevalence and antimicrobial susceptibility pattern of Staphylococcus haemolyticus isolates in hospitalized patients and their antimicrobial resistance pattern. The study comprised of 100 S. haemolyticus strains isolated from various clinical specimens. Antibiotic susceptibility was performed and interpreted as per standard protocols. Methicillin resistance was determined by minimum inhibitory concentration of oxacillin by macro broth dilution test. Susceptibility to glycopeptides (vancomycin and teicoplanin) was determined by broth macro dilution method. High level of resistance was found to various antibiotics tested. Methicillin resistance was found in 56% of S. haemolyticus strains. All the study isolates were susceptible to vancomycin and teicoplanin. Judicious use of antimicrobials with continuous monitoring of MIC levels of glycopeptides and effective infection control practices could help prevent emergence of resistance to these agents.
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