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Antibody isotype responses to egg antigens in human chronic Schistosomiasis mansoni before and after treatment

Author(s): Gomes Yara M | Pereira Valéria RA | Nakazawa Mineo | Montarroyos Ulisses | Souza Wayner V | Abath Frederico GC

Journal: Memórias do Instituto Oswaldo Cruz
ISSN 0074-0276

Volume: 97;
Issue: suppl.1;
Start page: 111;
Date: 2002;
Original page

Keywords: schistosomiasis | antibodies | treatment

In the present communication we analyzed the levels of IgG1, IgG2, IgG3, IgG4 and IgE isotypes to soluble egg antigen of Schistosoma mansoni by ELISA in individuals from an endemic area for schistosomiasis in Northeast Brazil. The analysis was performed before and after treatment to evaluate the age-dependent pattern, and to identify differences in the reactivities to antigens. Our results suggest that schistosomiasis treatment would not interfere with this sort of immune response.
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