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Antigenotoxic evaluation of Erythroxylum minutifolium griseb etanolic extract using SOS assay

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Author(s): Osney Leyva | Alena Alonso | Luis Alfredo Rosario Fernández | Adriana Díaz | Yalena Prado | Idania Rodeiro | Daniel Francisco Arencibia

Journal: RETEL : Revista de Toxicología en Línea
ISSN 1668-091X

Volume: 26;
Start page: 36;
Date: 2010;
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Keywords: antigenotoxicity | Erythroxylum | flavonoid | SOS assay

ABSTRACT
Plants have been used since remotes times for the treatment of different diseases.Under the name of Erythroxylum or Erythroxylon like genus, in Cuba are described 22 species. Some of these plants have been used in the traditional medicine due to its pharmacological properties. In this work the antigenotoxic potential of an etanolic extract of Erythroxylum minutifolium var Griseb (ExM) was analized using a modified protocol of the SOS Chromotest, co-treatment variant. Results showed that Erythroxylum minutifolium extract was antigenotoxic at the concentration of 100 ug/ml in the cells of E. coli PQ37. Results obtained can be influenced by the extract composition.
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