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Antihepatotoxic Effect of Feronia Limonia Fruit against Carbon Tetrachloride Induced Hepatic Damage in Albino Rats

Author(s): Rucha Upadhyay | Narendra Deo Pandey | Shahid Suhail Narvi | Amita Verma | Bahar Ahmed

Journal: Chinese Medicine
ISSN 2151-1918

Volume: 01;
Issue: 01;
Start page: 18;
Date: 2010;
Original page

Keywords: Anti-Hepatotoxic | Carbon Tetrachloride | Feronia Limonia Swingle

Feronia limonia Swingle, though mentioned as a high utility medicinal plant in Ayurveda for the treat-ment of liver disorders, but has no scientific investigations. Therefore, the present study was undertaken to investigate the hepatoprotective activity of extracts of Feronia limonia fruit on albino rat liver, damage induced by single dose of carbon-tetrachloride (1.5 ml/kg, p.o.). The oral administration of extracts (500 mg/kg, p.o.) for 7 days has shown significant hepatoprotective action. There is reduction in the elevated levels of serum enzymes such SGOT, SGPT, ALP and Serum bilirubin and elevation in level of GSH, GPX,GLY and total protein in Feronia limonia protected rats.
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