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Antilithiatic effect of flowers of Jasminum Auriculatum Vahl

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Author(s): Bahuguna Yogendr | Rawat Mohan Singh | Juyal Vijay | Gupta Vikas

Journal: International Journal of Green Pharmacy
ISSN 0973-8258

Volume: 3;
Issue: 2;
Start page: 155;
Date: 2009;
Original page

Keywords: Ethylene glycol | flowers | hyperoxaluria | Jasminum auriculatum | nephrolithiasis

ABSTRACT
The effect of oral administration of aqueous and alcohol extracts of Jasminum auriculatum Vahl (Oleaceae) flowers on calcium oxalate nephrolithiasis has been studied in male albino rats. Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate. Supplementation with aqueous and alcohol extract of J. auriculatum flowers significantly reduced the elevated urinary oxalate, showing a regulatory action on endogenous oxalate synthesis. The increased deposition of stone forming constituents in the kidneys of calculogenic rats was significantly lowered by curative and preventive treatment using aqueous and alcohol extracts. The results indicate that the flowers of J. auriculatum are endowed with antiurolithiatic activity.
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