Academic Journals Database
Disseminating quality controlled scientific knowledge

Antimicrobial Peptides from the Marine Fishes

ADD TO MY LIST
 
Author(s): S. Ravichandran | K. Kumaravel | G. Rameshkumar | T.T. AjithKumar

Journal: Research Journal of Immunology
ISSN 1994-7909

Volume: 3;
Issue: 2;
Start page: 146;
Date: 2010;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: mucous | antimicrobial peptide | Marine fishes | immunity | bacteria

ABSTRACT
Fishes are one of the organisms that have managed to survive in a milieu of pathogenic organisms. The primary interference of fish with their environment happens through a mucous layer that covers its entire body. Marine fishes possess antimicrobial peptides as a part of their defense system, which are mainly present in the mucous layer indicating that they eliminate the pathogenic bacteria before they enter the skin barrier. A number of α-helical Antimicrobial Peptides (AMP) such as Pardaxins, Misgurin, Pleurocidins, Parasin, Oncorhyncin II and III, Chrysophsin and HFIAP (Hagfish Intestinal Antimicrobial Peptide) have been isolated from different species of fishes. However, studies on the role of antimicrobial peptides in fishes are very limit. Various mechanisms developed by multicellular organisms in nonspecific immunity raises questions on the role of antibiotic peptide as a deterrent against infection. The present study provides a general introduction to the subject with special emphasis on the role of bioactive peptides in marine fishes.
Save time & money - Smart Internet Solutions      Why do you need a reservation system?