Academic Journals Database
Disseminating quality controlled scientific knowledge

Antinociceptive, anti-inflammatory and antidiarrheal activities of ethanolic calyx extract of Hibiscus sabdariffa Linn. (Malvaceae) in mice

ADD TO MY LIST
 
Author(s): Md. Khadem Ali | Shamima Afroz

Journal: Zhong Xi Yi Jie He Xue Bao
ISSN 1672-1977

Volume: 9;
Issue: 6;
Start page: 626;
Date: 2011;
Original page

Keywords: Hibiscus | plant extracts | analgesics | anti-inflammatory agents | antidiarrheals | mice

ABSTRACT
Objective: To evaluate the antinociceptive, anti-inflammatory and antidiarrheal activities of the ethanolic calyx extract of Hibiscus sabdariffa Linn. in mice.Methods: In the present study, the dried calyxes of H.  sabdariffa were subjected to extraction with 95% ethanol and the extract was used to investigate the possible activities. Antinociceptive activity of the extract was evaluated by using the acetic acid-induced writhing test. The anti-inflammatory effect of the extract was tested by using the xylene-induced ear edema model mice. Castor oil-induced diarrheal model mice were used to evaluate the antidiarrheal activity of the extract.Results: In acetic acid-induced writhing test, the extract produced inhibited writhing in mice siginificantly compared with the blank control (P
Affiliate Program      Why do you need a reservation system?