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ANTIOXIDANT ACTIVITIES OF METHANOLIC AND AQUEOUS EXTRACT OF MACROSOLEN PARASITICUS (L.) DANSER

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Author(s): Sodde Vijay | Dashora Nipun | Prabhu Kirti | Lobo Richard

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 2;
Issue: 1;
Start page: 207;
Date: 2011;
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Keywords: Antioxidant | Macrosolen parasiticus | DPPH | ABTS | phenolic compounds | flavonoids.

ABSTRACT
Macrosolen parasiticus (L.) Danser a parasitic plant belongs to the family Loranthaceae commonly known as mistletoes. The family comprises about 60 genera and 700 species and is widely distributed in all tropical regions and also in the southern land masses. Its species are mostly woody perennials which occur as aerial parasites of other dicotyledons.The present study describes the in vitro antioxidant study of methanolic and aqueous extract of the stem Macrosolen parasiticus (L.) Danser by DPPH, Superoxide scavenging, Reducing power, O-phenanthroline assay and nitric oxide scavenging, and both extracts showed good free radical scavenging property. IC50 values of methanolic and aqueous extracts were found to be 79.67 and 54.32 µg/ml for DPPH, 50.12 and 35.12 µg/ml for Superoxide scavenging, 40.08 and 28.56 µg/ml for Reducing power,86.65 and 83.39 µg/ml for O-phenanthroline assay and 152.53 and 102.43 µg/ml nitric oxide, when compared with ascorbic acid having IC50 values 13.15, 5.45, 9.15, 13.43 and 23.87 µg/ml for DPPH, super oxide, reducing power, O-phenanthroline assay and nitric oxide respectively. Macrosolen parasiticus stem extracts exhibited moderate free radical scavenging activity. The overall antioxidant activity might be attributed to its phenolic compounds, falvonoides and other phytochemical constituents. The findings suggest that Macrosolen parasiticus could be a source of natural antioxidant in preventing age associated oxidative stress related degenerative diseases.
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