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Antioxidant and anti inflammatory activities of the root of Mussaenda glabrata.

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Author(s): Darsan B Menon* and J. M. Sasikumar

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 10;
Start page: 3320;
Date: 2011;
Original page

Keywords: Anti oxidant activity | Anti inflammatory activity | Mussaenda glabrata

ABSTRACT
The in vitro anti oxidant and anti inflammatory activities of the methanolic extract of Mussaenda glabrata roots were tested. The phytochemical screeningrevealed the presence of alkaloids, phenols, tannins, proteins, carbohydrates, saponins, glycosides and cardiac glycosides. The extract showed good DPPH (1, 1-diphenyl-2-picrylhydrazyl) radical scavenging activity. Ascorbic acid and Gallic acids were used as standard antioxidants and positive controls. The extract at lowerconcentrations exhibited good anti inflammatory activity as well compared to the standard anti inflammatory drugs Diclofenac and Hydrocortisone. The studysuggests that Mussaenda glabrata could be pharmaceutically exploited for its antioxidant and anti inflammatory properties.
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