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ANTISPASMODIC STUDIES ON LEAF EXTRACT OF ERYTHRINA INDICA LAM

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Author(s): R. Kamalraj | G. Devdass

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 2;
Issue: 4;
Start page: 1380;
Date: 2011;
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Keywords: Antispasmodic activity | Erythrina indica Lam | guinea pig | Ileum.

ABSTRACT
The aim of the present investigation to evaluate the antispasmodic activity of Erythrina indica leaf, an indigenous plant used in ayurvedic medicine in India. The antispasmodic effect of hexane extracts of Erythrina indica Leaf were studied in vitro in guinea pig ileum against three spasmogens; acetylcholine, histamine and barium chloride. The hexane extract produces a significant antispasmodic effect on the contractions of the guinea pig ileum induced by acetylcholine, histamine and barium chloride. The inhibitory concentration for each was determined. These results show that hexane extract of Erythrina indica Leaf possesses antispasmodic properties.

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