Academic Journals Database
Disseminating quality controlled scientific knowledge

Antiviral Activity and Constituents of the Nepalese Medicinal Plant Astilbe rivularis

Author(s): Meena Rajbhandari | Michael Lalk | Renate Mentel | Ulrike Lindequist

Journal: Records of Natural Products
ISSN 1307-6167

Volume: 5;
Issue: 2;
Start page: 138;
Date: 2011;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: Astilbe rivularis | antiviral | arbutin | bergenin | dimer of bergenin.

During the screening of Nepalese ethnomedicinal plants for antiviral activities, Astilbe rivularis Buch.-Ham. , Saxifragaceae, was identified as a promising species. Bioassay-guided fractionation led to the isolation of arbutin, bergenin and a bergenin derivative. The structures were established by NMR studies. Except bergenin, the two compounds were found in this plant for the first time. A dimer of bergenin has not been described as a natural product before. The compounds showed in vitro antiviral activity against herpes simplex virus type-1 in non cytotoxic concentrations.
Affiliate Program     

Tango Rapperswil
Tango Rapperswil