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Aqueous fish extract increases survival in the mouse model of cytostatic toxicity

Author(s): Omerovic Elmir | Linbom Malin | Råmunddal Truls | Lindgård Ann | Undeland Ingrid | Sandberg Ann-Sofie | Soussi Bassam

Journal: Journal of Experimental & Clinical Cancer Research
ISSN 1756-9966

Volume: 27;
Issue: 1;
Start page: 81;
Date: 2008;
Original page

Abstract Background Treatment of cancer patients with anthracycline antibiotic doxorubicin (DOX) may be complicated by development of acute and chronic congestive heart failure (CHF), malignant arrhythmias and death. The aim of this study was to test whether an aqueous low molecular weight (LMW) extract from cod muscle decreases acute mortality in the mouse model of acute CHF caused by DOX. Methods A LMW fraction (
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