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Aromatase enzyme (P450arom) mRNA expression in mouse gonads and the effect of intra-peritoneal amino acid injection

Author(s): Hüseyin Baki Çiftci

Journal: Research Opinions in Animal & Veterinary Sciences
ISSN 2221-1896

Volume: 1;
Issue: 7;
Start page: 410;
Date: 2011;
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Keywords: Aromatase Enzyme | Amino Acid | Gonad | mRNA | Mouse

The aim of this study was show the presence of (P450arom) mRNA expressions in mouse gonads and to measure the effect of intra-peritoneal serine/threonine or glycine injections on the expression of aromatase enzyme P450arommRNA. Three different (1.4, 2.4 and 4.4kb) P450arom mRNA species were indentified in mouse testis and the ovary. Relative to saline injected group (S), all the species of P450arom enzyme mRNA decreased in serine/threonine (A) or glycine (G) injected female mice, while all of them were increased in male. Aromatase enzyme mRNA expression is differently regulated in male and female mice.
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