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Assessment of diabetes risk in men with different levels of cardiovascular risk

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Author(s): M.N. Kovrigina | M.N. Mamedov

Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii
ISSN 1819-6446

Volume: 8;
Issue: 6;
Start page: 766;
Date: 2012;
Original page

Keywords: early glucose metabolism disturbances | cardiovascular diseases | diabetes mellitus 2 type

ABSTRACT
Aim. To assess the risk of diabetes mellitus type 2 (DM2) in patients with various cardiovascular (CV) risk, and to identify the relationship between a high risk of DM2 and the major CV risk factors.Material and methods. Men (n=378) with one or more CV risk factors (hypertension of stage 1–3, smoking, hypercholesterolemia) and various CV risk (SCORE) were included in the one-stage clinical trial. All patients were interviewed with standard questionnaire and FINDRISC questionnaire, as well as glucose tolerance test was performed.Results. The patients were split into three groups based on the total CV risk (SCORE): 33.6% had low-to-moderate CV risk, 38.9% — high CV risk and 27.5% — very high CV risk. Most of the men were in the 50–59 and 60–69 years age groups. Most of the patients aged 40–49 years had the high CV risk, while 59% of men aged 50–59 had moderate CV risk. Every second older male had a very high CV risk. According to the FINDRISC questionnaire low risk of DM2 in the next 10 years was detected in 40.2% of patients, intermediate risk — in 35.2%, moderate risk — in 10.3%, high risk — in 11.1%, a very high risk — in 3.2% of patients.Conclusion. Men with very high CV risk (SCORE) have also high and very high risk of DM2 (according to FINDRISC questionnaire). Detection of early markers of glucose metabolism disturbances as well as DM2 risk assessment should be performed in patients with one or more of the above mentioned CV risk factors. This strategy is able to contribute to proper DM2 risk assessment and development of methods of DM2 prevention.

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