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Association of Acromegaly and Multiple Myeloma: A Case Report

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Author(s): Murat Atmaca | Saliha Yıldız | Işılay Kalan | Mehmet Fatih Özbay | İsmet Seven | Mustafa Öztürk

Journal: Turkish Journal of Endocrinology and Metabolism
ISSN 1301-2193

Volume: 17;
Issue: 3;
Start page: 75;
Date: 2013;
Original page

Keywords: Acromegaly | multiple myeloma

ABSTRACT
Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare in acromegaly. Here, we report an 80-year-old patient with acromegaly and multiple myeloma. Patient died within a month of diagnosis. Previous studies have shown that growth hormone and somatomedin-C activate B lymphocyte and somatomedin-C receptors are found in multiple myeloma cells. Possible effects of growth hormone and somatomedin-C on multiple myeloma progression are discussed in the light of the relevant literature. Turk Jem 2013; 17: 75-7

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