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Associations between diet and disease activity in ulcerative colitis patients using a novel method of data analysis

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Author(s): Magee Elizabeth | Edmond Laurie | Tasker Shiona | Kong San | Curno Richard | Cummings John

Journal: Nutrition Journal
ISSN 1475-2891

Volume: 4;
Issue: 1;
Start page: 7;
Date: 2005;
Original page

Keywords: ulcerative colitis | diet | sulfite | thiamin | resistant starch

ABSTRACT
Abstract Background The relapsing nature and varying geographical prevalence of ulcerative colitis (UC) implicates environmental factors such as diet in its aetiology. Methods In order to determine which foods might be related to disease activity in UC a new method of dietary analysis was developed and applied. Eighty-one UC patients were recruited at all stages of the disease process. Following completion of a 7 d diet diary, clinical assessment including a sigmoidoscopic examination (scale 0 (normal mucosa) to 6 (very active disease)) was conducted. Food weights for each person were adjusted (divided) by the person's calorific intake for the week. Each food consumed was given a food sigmoidoscopy score (FSS) calculated by summing the products of the (adjusted) weight of food consumed and sigmoidoscopy score for each patient and occurrence of food and dividing by the total (adjusted) weight of the food consumed by all 81 patients. Thus, foods eaten in large quantities by patients with very active disease have high FSSs and vice versa. Foods consumed by

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