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Associative Tolerance of Intravenously Administered Lipid and Gestational Age in Preterm Infants Receiving Total Parenteral Nutrition

Author(s): Snezhana Palchevska-Kocevska | Ljiljana Kojik

Journal: Macedonian Journal of Medical Sciences
ISSN 1857-5749

Volume: 2;
Issue: 1;
Start page: 63;
Date: 2009;
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Keywords: Total parenteral nutrition | preterm infants | serum triglyceride | birth weight | gestational age.

Aim. The aim of this study is to investigate the effect of constant amount of lipid during total parenteral nutrition (TPN), by the evaluation of serum levels of: total cholesterol, triglycerides, free fatty acids, billirubin, AST, ALT, acid base status in the group of sick preterm infants.Material and methods. The tolerance for intravenously administered lipid (IL), with a maximal daily dose of 2.5 gr/kg, in 20 sick preterm infants during total parenteral nutrition was analyzed by controlling the total serum lipid level; the total cholesterol; the serum triglycerides concentration; the free fatty acids levels; the lipoprotein electrophoresis; the bilirubin level (total, conjugated and unconjugated); ALT and AST; the blood hemoglobin; erythrocyte, leukocyte and reticulocyte count; hematocrit; and the acid base status in capillary, venous and arterial blood. Results. A serum triglyceride concentration 2.0 mmol/l in 2 (10%). Hypertriglyceridemia >1.5 mmol/l was found in 4 patients with perinatal asphyxia and one with septicemia. There is a highly significant inverse correlation (p
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