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Associative Tolerance of Intravenously Administered Lipid and Gestational Age in Preterm Infants Receiving Total Parenteral Nutrition

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Author(s): Snezhana Palchevska-Kocevska | Ljiljana Kojik

Journal: Macedonian Journal of Medical Sciences
ISSN 1857-5749

Volume: 2;
Issue: 1;
Start page: 63;
Date: 2009;
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Keywords: Total parenteral nutrition | preterm infants | serum triglyceride | birth weight | gestational age.

ABSTRACT
Aim. The aim of this study is to investigate the effect of constant amount of lipid during total parenteral nutrition (TPN), by the evaluation of serum levels of: total cholesterol, triglycerides, free fatty acids, billirubin, AST, ALT, acid base status in the group of sick preterm infants.Material and methods. The tolerance for intravenously administered lipid (IL), with a maximal daily dose of 2.5 gr/kg, in 20 sick preterm infants during total parenteral nutrition was analyzed by controlling the total serum lipid level; the total cholesterol; the serum triglycerides concentration; the free fatty acids levels; the lipoprotein electrophoresis; the bilirubin level (total, conjugated and unconjugated); ALT and AST; the blood hemoglobin; erythrocyte, leukocyte and reticulocyte count; hematocrit; and the acid base status in capillary, venous and arterial blood. Results. A serum triglyceride concentration 2.0 mmol/l in 2 (10%). Hypertriglyceridemia >1.5 mmol/l was found in 4 patients with perinatal asphyxia and one with septicemia. There is a highly significant inverse correlation (p
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