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Autoimmune Inner Ear Disease- A Clinical Viewpoint

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Author(s): Amirala Khalessi | Pedram Borghei | Mohammad Hassan Khalessi

Journal: Iranian Journal of Otorhinolaryngology
ISSN 2251-7251

Volume: 22;
Issue: 61;
Start page: 111;
Date: 2010;
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Keywords: Autoimmune | Disease | Inner ear

ABSTRACT
Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic tools, and the important differential diagnoses will be summarized. The management methods, including steroid therapy, immunosuppressive medications, other biological agents and intra-tympanic injections, will be addressed. Cochlear implantation as a final solution to the advanced stages of the disease, causing total deafness, will also be discussed.
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