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Autologous Fibrin Sealant in Tubeless Percutaneous Nephrolithotomy; A Prospective Study

Author(s): Seyyed Amir Mohsen Ziaee, | Reza Sarhangnejad | Hassan Abolghasemi | Peyman Eshghi | Mohammad Hadi Radfar | Ali Ahanian | Muhammet Ihsan Karaman | Nasser Amirizadeh | Akbar Nouralizadeh

Journal: Urology Journal
ISSN 1735-1308

Volume: 10;
Issue: 3;
Start page: 999;
Date: 2013;
Original page

Keywords: Autologous Fibrin | Percutaneous Nephrolithotomy

Purpose: To evaluate the efficacy of autologous single-donor fibrin glue after tubeless percutaneousnephrolithotomy (PCNL).Materials and Methods: Forty-three patients were planned for tubeless PCNL in a prospectivecohort study and randomized in two groups with or without using fibrin glue. Randomizationmethod was based on the computer-generated random numbers.Results: Transfusion, urinary leakage, or major complications were found in neither of thegroups. There was no difference between two groups in stone free rate (P = .53), and changesin hemoglobin (P = .61) and serum creatinine (P = .63) level.Conclusion: Although autologous fibrin glue did not play any significant role in improvingresults or decreasing complications after tubeless PCNL in our study, its use was safe and didnot increase complications.Keywords: percutaneous; surgery; kidney calculi, treatment outcome; fibrin tissue adhesive;wound closure techniques
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