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Bilateral Hyperkeratosis Of Nipple And Areolae Mammaes: A Case Report

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Author(s): Mortazavi Ht Asadi Kani Z

Journal: Tehran University Medical Journal
ISSN 1683-1764

Volume: 60;
Issue: 1;
Start page: 64;
Date: 2002;
Original page

Keywords: Hyperkeratosis | nipple | mammae | nevoid

ABSTRACT
A 25-year-old woman with a history of five years of bilateral verrucous hyperkeratosis and darkening of both nipples and areolae is reported herein. The histopathology was suggestive of hyperkeratosis of areola and nipple. Hyperkeratosis of areola and nipple is a rare condition which is seen unilaterally or bilaterally in both sexes. Three types of hyperkeratosis of areola and nipple are described: type I is literally the extension of epidermal nevus, type II is associated with ichthyosis and acanthosis nigricans, and type III is an idiopathic or isolated nevoid form. The patient presented herein is a case of bilateral hyperkeratosis of areolae and nipples associated with benign acanthosis nigricans. In other words, the patient was suffering from type II hyperkeratosis of areolae and nipples.
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