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Biochemical markers of bone metabolism in dairy cows with milk fever

Author(s): Starič J. | Zadnik T.

Journal: Acta Veterinaria
ISSN 0567-8315

Volume: 60;
Issue: 4;
Start page: 401;
Date: 2010;
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Keywords: biomarkers | blood | bone metabolism | cattle | milk fever

Bone metabolism was investigated in 8 healthy and 12 dairy cows suffering from milk fever (MF) in intensive dairy production. Blood samples were taken within 48 hours after calving in healthy cows and before treatment in cows with MF. Bone and mineral metabolism were evaluated by measuring blood serum bone resorption biomarker Cterminal telopeptide of type I collagen (CTx) and bone formation biomarker bone-specific alkaline phosphatase (bALP) beside the classical panel: total calcium (Ca), inorganic phosphate (iP), magnesium (Mg) and alkaline phosphatase (ALP). The results were statistically analyzed and compared between the two groups. Mean Ca value in cows with milk fever was 1.01±0.29 mmol/L and in healthy cows it was significantly (p
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