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BIPOLAR DISORDER: A REVIEW

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Author(s): Pathan Dilnawaz N | Ziyaurrahaman A.R | Bhise K.S.

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 1;
Issue: 2;
Start page: 327;
Date: 2010;
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Keywords: Bipolar disorder | depression | mood disorder | psychotherapy.

ABSTRACT
Bipolar disorder (BD) is a severe psychiatric disorder that results in poor global functioning, reduced quality of life and high relapse rates. Research finds that many adults with bipolar disorder identify the onset of symptoms in childhood and adolescence, indicating the importance of early accurate diagnosis and treatment. Accurate diagnosis of mood disorders is critical for treatment to be effective. Distinguishing between major depression and bipolar disorders, especially the depressed phase of a bipolar disorder, is essential, because they differ substantially in their genetics, clinical course, outcomes, prognosis, and treatment. In current practice, bipolar disorders, especially bipolar II disorder, are under diagnosed. Misdiagnosing bipolar disorders deprives patients of timely and potentially lifesaving treatment, particularly considering the development of newer and possibly more effective medications for both depressive features and the maintenance treatment (prevention of recurrence/relapse). Without treatment, patients with bipolar disorder face substantial distress and impairment and have a significant risk of morbidity and mortality. Traditionally, lithium has been considered the treatment of choice for bipolar disorder. However, more recently, valproic acid has become an increasingly popular alternative to lithium as a first-line treatment. Treatment adherence is a frequent problem in bipolar disorder, with research showing that more than 60% of bipolar patients are at least partially nonadherent to medications. Several types of adjunctive treatment (family, psychoeducational, cognitive-behavioral) have been investigated for improving symptoms and functioning in bipolar patients with some success.
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