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Blood Glucose Lowering Potential of Stem Bark of Berberis aristata Dc in Alloxan-Induced Diabetic Rats

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Author(s): J. Kumar Gupta | P. Mishra | Asha Rani | P. Mitra Mazumder

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 9;
Issue: 1;
Start page: 21;
Date: 2010;
Original page

Keywords: Antidiabetc Activity | Antioxidant | Berberis Aristata | Methanolic Extract | Alloxan | Phenolic Content

ABSTRACT
The present investigation explores the blood glucose lowering potential of Berberis aristata stem bark extract (methanolic extract) in alloxan-induced diabetic rats as well as its in vitro antioxidant property. It is observed that methanolic extract of B. aristata stem bark exhibits significant antidiabetic activity in a dose-dependent manner, but not better than glibenclamide. The extract also has enough reducing power to manifest its antioxidant nature.

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