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Blood supply of the insular cortex of Cercopithecus Aethiops: Another approach to establish non-human primate model for addiction

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Author(s): Filipović Branislav | Dimitrijević I. | Đulejić V. | Krstić M. | Jurišić A. | Kalezić Nevena | Teofilovski-Parapid Gordana

Journal: Acta Veterinaria
ISSN 0567-8315

Volume: 58;
Issue: 2-3;
Start page: 121;
Date: 2008;
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Keywords: insula | blood supply | Cercopithecus Aethiops | addiction | non-human primate model

ABSTRACT
The non-human primate model has already been applied in studies about alcoholism in the last decade, demonstrating a high confidence level of similarities between humans and non-human monkeys. Authors indented to establish the definitive model for addiction by investigating the insular blood supply in Cercopithecus Aethiops. In 23 out of 24 Latex injected adult brains, the insula received blood supplied by the M2 segment of the middle cerebral artery (MCA). The cortex was supplied by two separate trunks, while perforating branches originating directly from MCA, individually, or together with lateral striate (lenticulostriate) arteries. Their average caliber was about 120 µm, and the number of its branches ranged from 2 to 9. No left - right asymmetries have been recorded. Similarities with the human vascular pattern have been studied. .
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