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Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories

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Author(s): Dagieli Sartor | Natália Gindri Fiorenza | Jociane de Carvalho Myskiw | Iván Izquierdo

Journal: Neuroscience & Medicine
ISSN 2158-2912

Volume: 02;
Issue: 03;
Start page: 232;
Date: 2011;
Original page

Keywords: Memory | Extinction Learning | Reconsolidation | Fear Memories

ABSTRACT
Memory traces become labile at the time of retrieval, and this initiates two protein synthesis-dependent processes in the brain: extinction, which inhibits their further retrieval, and reconsolidation, which may enhance retrieval or change the memory’s content. Extinction may itself suffer reconsolidation. Interactions between these processes may be applied to the treatment of fear memories, such as those underlying the post-traumatic stress disorder.
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