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Brain natriuretic peptide: Diagnostic potential in dogs

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Author(s): Spasojević-Kosić Ljubica

Journal: Veterinarski Glasnik
ISSN 0350-2457

Volume: 63;
Issue: 5-6;
Start page: 381;
Date: 2009;
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Keywords: heart diseases | cardiac insufficiency | diagnostics | BNP | dog

ABSTRACT
The endocrine role of the heart is evident in the secretion of noradrenaline and natriuretic peptides. The secretion of natriuretic peptides presents a useful mechanism for different conditions of cardiac dysfunction. Brain natriuretic peptide (BNP) has been accepted in human cardiology as a biomarker for cardiac insufficiency and coronary arterial disease. The specificity of the BNP structure is specie-specific, so that the testing of diagnostic and prognostic potential in dogs requires the existence of a test that is a homologue for that animal specie. The existence of an adequate method for measuring BNP concentration makes possible its implementation as a screening test in everyday clinical practice. .
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