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Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy

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Author(s): Yi Zhang | Jun Mu | Yan Feng | Yue Kang | Jia Zhang | Peng-Juan Gu | Yu Wang | Li-Fang Ma | Yan-Hua Zhu

Journal: Marine Drugs
ISSN 1660-3397

Volume: 7;
Issue: 2;
Start page: 97;
Date: 2009;
Original page

Keywords: Epi- and endophytic | marine derived fungi | antimicrobial activity | taxonomy

ABSTRACT
In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata.
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