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Butorphanol premedication to facilitate invasive monitoring in cardiac surgery patients before induction of anaesthesia

Author(s): Tripathi Mukesh | Nath Soumya | Banerjee Sudipto | Tripathi Mamta

Journal: Annals of Cardiac Anaesthesia
ISSN 0971-9784

Volume: 12;
Issue: 1;
Start page: 34;
Date: 2009;
Original page

Keywords: Butorphanol | cardiac surgery | internal jugular vein cannulation | pain | premedication | radial artery cannulation

Cannulations (peripheral vein, radial artery and jugular vein) performed for invasive monitoring before induction of anaesthesia in cardiac surgery patients may be associated with stress and anxiety. The efficacy and safety of butorphanol premedication was assessed in setting up of invasive monitoring. The study was a prospective, randomized, double blind, placebo controlled one with 70 patients undergoing elective cardiac surgery. In group-1 patients ( n = 35) (placebo) intramuscular saline was administered 1-2 hours before the surgery in equivalent volume to butorphanol. In group-2 ( n = 35) butorphanol (1, 1.5 and 2 mg for three body weight groups < 40 kg, 41-60 kg and> 60 kg, respectively) was administered 1-2 hours before surgery. Observer blinded for medication recorded the sedation score, pupil size and pain after each cannulation using visual analogue score (VAS). Student′s ′ t ′ test and Chi-square test for proportions, Mann-Whitney test for non-parametric data was carried out. The median pain score of cannulation in group-2 (butorphanol) in the hand (10 mm) and neck (20 mm) were significantly ( P