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Capillaroscopic assessment of vascular changes in psoriasis vulgaris and psoriatic arthritis. Kapilaroskopowa ocena zmian naczyniowych w łuszczycy zwyczajnej i stawowej.

Author(s): Joanna Bartosińska | Grażyna Chodorowska | Maria Juszkiewicz-Borowiec | Bartłomiej Wawrzynki | Jakub Chodorowski | Anna Michalak-Stoma

Journal: Clinical Dermatology
ISSN 1730-7201

Volume: 12;
Issue: 2;
Start page: 85;
Date: 2010;
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Keywords: łuszczyca | łuszczyca stawowa | kapilary | nieprawidłowa angiogeneza | psoriasis | psoriatic arthritis | capillaries | pathologic angiogenesis

Background: In the process of psoriatic plaque formation numerous morphological and functional abnormalities, including microvascular changes, are observed. Similar vascular abnormalities occur within the synovial membrane of patients with psoriatic arthritis. Capillaroscopy is a diagnostic procedure which allows for visualization of quantitative and qualitative changes within the capillaries. Objectives: The aim of the study was assessment of vascular changes in psoriasis vulgaris as well as psoriatic arthritis with emphasis to capillaroscopic differences in these two types of diseases. Material and methods: The study included 111 adult psoriatic patients. 53 patients suffered from psoriatic arthritis while 58 patients had psoriasis vulgaris. Nailfold capillaroscopies of II to V fingers of both hands were performed. Results: 16.98% of patients with psoriatic arthritis presented pale a capillaroscopic background, which was not observed in patients with psoriasis vulgaris. Sub- -papillary venular plexus was visible significantly more frequently in patients with psoriatic arthritis (p=0.032). In 30.19% of patients with psoriatic arthritis a decreased number of nailfold capillaries was found. 43.40% of patients with psoriatic arthritis and 24.14% of patients with psoriasis vulgaris had thin nailfold capillaries. Frail nailfold capillaries were found only in patients with psoriatic arthritis (16.93%). No statistically significant differences were detected between the group of patients with psoriatic arthritis and those with psoriasis vulgaris with regard to the frequency of changes in the shape and contour of the vascular loop (p>0.05). Conclusions: Patients suffering from both types of diseases i.e. psoriatic arthritis and psoriasis vulgaris, presented specific microcirculatory abnormalities. However more severe capillaroscopic changes were found in psoriatic arthritis patients in comparison with patients with psoriasis vulgaris.
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