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Cardiovascular Risk in women with Metabolic Syndrome Aumento do Risco Cardiovascular em Mulheres com Síndrome Metabólica

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Author(s): Rosimere J. Teixeira | Ana Borba Leite | Clarice A.S.A Farias | Cíntia R. Sousa | Adryana M. Yugue | Aline A. Aguiar | Denise Ginzbarg | Maria Inez A. Padula

Journal: Revista Brasileira de Medicina de Família e Comunidade
ISSN 1809-5909

Volume: 3;
Issue: 12;
Start page: 237;
Date: 2010;
Original page

Keywords: Resistência à Insulina | Síndrome Metabólica | Saúde da Mulher

ABSTRACT
Today, the metabolic syndrome (MS) epidemic turned into a public health problem. The true role of MS as a risk factor of cardiovascular disease however is not defined yet. Our objective was to describe the cardiovascular risk (CVR) in 45 women with (n=25, 51±12years) and without MS (n=20, 36±13years). BMI, abdominal circumference and systolic and diastolic blood pressure (SBP and DBP) were evaluated. The levels of fasting glucose (G) and insulin, post-prandial G (ppG), triglycerides, cholesterol, HDL and LDL were measured. Insulin sensibility was evaluated using the IRHoma method. SM was defined according to the National Cholesterol Education Program. The CVR was calculated according to the Framingham score and classified as low, medium and high. The abdominal circumference and SBP were significantly higher in SM, but there were no differences in relation to the BMI and DBP. G, Gpp and triglyceride levels were significantly higher, while the HDL was lower in MS. The number of components, CVR and the proportion of cases with medium or high risk were higher in the MS. CVR was correlated with the number of components (r=0,62), circumference (r=0,45), G (r=0,72), SBP (r= 0,59) and HDL (r=-0,31) and in the multiple regression analysis only with G and SBP (r2=0,67, p
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