Academic Journals Database
Disseminating quality controlled scientific knowledge

A case report of acute dermatitis that developed during an experiment examining the bromination of 3-hexylthiophene

ADD TO MY LIST
 
Author(s): Sato Mikiya | Yoshiki Hajime | Horie Masaki | Yano Eiji

Journal: Journal of Occupational Medicine and Toxicology
ISSN 1745-6673

Volume: 5;
Issue: 1;
Start page: 3;
Date: 2010;
Original page

ABSTRACT
Abstract Occupational cases with allergic reaction to fragrance substances, which refer to various chemicals providing aroma characteristics, are arising with its recent usage diversification from pharmaceutical, perfume industry to aromatic remedies. However, chemicals responsible for fragrance allergy have hardly been identified because its component is complex and its sensitization is not frequent. This report will present a case of acute allergic dermatitis that is likely induced by 3-hexylthiophene, one of aromatic compounds often contained in fragrance substances. The case, who was a 27-year male researcher engaged in organic chemical synthesis for six years, was exposed to 3-hexylthiophene and its product (2-bromo-3-hexylthiophene) through an experiment in May 2004 and itching, swelling and eczema immediately developed from face to back. This case of sensitization to 3-hexylthiophene suggests that it be a possible allergen for fragrance allergy.

Tango Rapperswil
Tango Rapperswil

     Affiliate Program